POSITION AND HONORS 
 

1997 – 1998, Research Assistant, Department of Statistics, Texas A&M University, College Station, TX

1998 – 2000, Research Assistant, Nutrition Group, Texas A&M University, College Station, TX

2000 – Present, Assistant Professor, Department of Biostatistics, University of Texas MD Anderson Cancer   Center, Houston, TX 
 

Texas A&M University Graduate Merit Fellowship, 1995

Texas A&M College of Science Dean’s Graduate Fellowship, 1995

Engineering and Physical Sciences Research Council Visiting Fellowship, 2001

Travel Award for Young Researchers, Biometrics Section of ASA, 2001

Best Abstract, 1^st Annual Duke University Proteomics Data Mining Conference, 2002

JASA Applications and Case Studies Invited Paper Award, 2003

Mitchell Prize Award, 2003

Best Presentation, 4^th Duke University Critical Assessment of Microarray Data Analysis Meeting 2003 
 

SELECTED PEER-REVIEWED PUBLICATIONS 
 

Hong MY, Chapkin RS, Wild CP, Morris JS, Wang N, Carroll RJ, Turner ND and Lupton JR:  Relationship Between DNA Adduct Levels, Repair Enzyme and Apoptosis as a Function of DNA Alkylation by Azoxymethane.  Cell Growth and Differentiation 10: 749-758, 1999.

Davidson LA, Brown RE, Chang W-CL, Lupton JR, Morris JS, Wang N, Carroll, RJ, Turner, ND and Chapkin, RS:  Morphodensitometric Analysis of Protein Kinase C b_II Expression in the Rat Colon:  Modulation by Diet and Relation to in situ Cell Proliferation and Apoptosis.  Carcinogenesis 21: 1513-1519, 2000.

Hong MY, Lupton JR, Morris JS, Wang N, Carroll RJ, Davidson LA, Elder R and Chapkin RS:  Dietary Fish Oil Reduces 0⁶-methylguanine DNA Adduct Levels in the Rat Colon In Part By Increasing Apoptosis During Tumor Initiation.  Cancer Epidemiology, Biomarkers and Prevention 9: 819-826, 2000.

Shureiqi I, Xu X, Chen D, Lotan R, Morris JS, Fischer SM and Lippman SM:  Nonsteroidal Anti-inflammatory Drugs Induce Apoptosis in Esophageal Cancer Cells by Restoring 15-Lipoxygenase-1 Expression.  Cancer Research 61: 4879-4884, 2001.

Arrington JL, Chapkin RS, Switzer KC, Morris JS and McMurray DN:  Dietary n-3 Polyunsaturated Fatty Acids Modulate Purified Murine T-cell Subset Activation.  Clinical and Experimental Immunology 125: 499-507, 2001.

Hong MY, Chapkin RS, Morris JS, Wang N, Carroll RJ, Turner ND, Chang WCL, Davidson FA and Lupton JR:  Anatomical Site-Specific Response to DNA Damage is Related to Later Tumor Development in the Rat AOM Colon Carcinogenesis Model.   Carcinogenesis 22:1831-1835, 2001.

Shureiqi I, Cook CD, Morris JS, Soliman AS, Levin B, and Lippman SM: Effect of Age on Risk of Second Primary Colorectal Cancer.  Journal of the National Cancer Institute 93: 1264-1265, 2001.

Rashid A, Lanlan S, Morris JS, Issa J-PJ, Hamilton SR: CpG island methylation in colorectal adenomas. The American Journal of Pathology 159:1129-1135, 2001.

Morris JS, Wang N, Lupton JR, Chapkin RS, Turner ND, Hong MY and Carroll RJ:  Parametric and Nonparametric Methods for Understanding the Relationship Between Carcinogen-Induced DNA Adduct Levels in Distal and Proximal Regions of the Colon.  Journal of the American Statistical Association 96:  816-826, 2001.

Chan AOO, Issa-J-PJ, Morris JS, Hamilton SR and Rashid A:  Concordant CpG Island Methylation in Hyperplastic Polyposis.  The American Journal of Pathology 160: 529-536, 2002.

Morris JS:  The BLUPs Are Not “Best” When It Comes To Bootstrapping.  Statistics and Probability Letters 56; 425-430, 2002.

Morris JS, Wang N, Lupton JR, Chapkin RS, Turner ND, Hong MY and Carroll RJ:  A Bayesian Analysis Involving Colonic Crypt Structure and Coordinated Response to Carcinogens Incorporating Missing Crypts, Biostatistics 3: 529-546, 2002.

Lin E, Morris JS and Ayers GD:  Effect of Celecoxib on Capecitabine-induced Hand-foot Syndrome and Antitumor Activity.  Oncology 16: supplement, 2002.

Madoff DC, Hicks ME, Abdalla EK, Morris JS and Vauthey JN:  Portal Vein Embolization Using Polyvinyl Alcohol Particles and Coils in Preparation for Major Liver Resection for Hepatobiliary Malignancy:  Safety and Efficacy:  A Study in 26 Patients.  Radiology 227: 251-260, 2003.

Switzer KC, McMurray DN, Morris, JS and Chapkin RS: N-3 Polyunsaturated Fatty Acids Promote Activation-induced Cell Death in Murine T Lymphocytes.  The Journal of Nutrition 133 (2):  496-503, 2003.

Morris JS, Baggerly K, and Coombes K: Bayesian Shrinkage Estimators of the Relative Abundance of mRNA Transcripts using SAGE.  Biometrics 59: 476-486, 2003.

Hong MY, Chapkin RS, Davidson LA, Turner ND, Morris JS, Carroll RJ and Lupton JR:  Fish Oil Enhances Targeted Apoptosis During Colon Tumor Initiation In Part by Downregulating BCL-2.  Nutrition and Cancer 46(1): 44-51, 2003.

Shureiqi I, Jiang W, Zuo X, Wu Y, Stimmel JB, Leesnitzer LM, Morris JS, Fan HZ, Fischer SM, Lippman SM: The 15-lipoxygenase-1 product 13-S-hydroxyocta-decadienoic acid down-regulates PPAR-{delta} to induce apoptosis in colorectal cancer cells. Proceedings of the National Academy of Sciences 100(17): 9968-9973, 2003.

Morris JS, Vannucci M, Brown PJ and Carroll RJ: Wavelet-Based Nonparametric Modeling of Hierarchical Functions in Colon Carcinogenesis.  Journal of the American Statistical Association 98: 573-583, 2003.

Morris JS, Vannucci M, Brown PF and Carroll RJ:  Rejoinder to Wavelet-Based Nonparametric Modeling of Hierarchical Functions in Colon Carcinogenesis.  Journal of the American Statistical Association98: 591-597, 2003.

Baggerly K, Deng L, Morris JS, Aldez CM:  Differential Expression in SAGE: Accounting for Normal Between-library Variation.  Bioinformatics 19: 1477-1483, 2003.

Baggerly K, Morris JS, Wang J, Gold D, Xiao LC and Coombes K:  A Comprehensive Approach to the Analysis of MALDI-TOF Proteomics Spectra from Serum Samples.  Proteomics: 3: 1667-1672, 2003.

Coombes KR, Fritsche HA Jr., Clarke C., Cheng JN, Baggerly KA, Morris JS, Xiao LC, Hung MC and Kuerer HM:  Quality Control and Peak Finding for Proteomics Data Collected from Nipple Aspirate Fluid Using Surface Enhanced Laser Desorption and Ionization.  Clinical Chemistry 49(10): 1615-1623, 2003.

Pawlik TM, Izzo F, Cohen DS, Morris JS, and Curley SA: Combined resection and radiofrequency ablation for advanced hepatic malignancies: Results in 172 patients.  Journal of Surgical Oncology 10(9): 1059-1069, 2003.

Pawlik TM, Paulino AF, Mcginn CJ, Baker LH, Cohen DS, Morris JS, Rees R, and Sondak VK: Cutaneous angiosarcoma of the scalp: A multidisciplinary approach.  Cancer 98(8): 1716-1726, 2003.

Morris JS, Wang N, Lupton JR, Chapkin RS, Turner ND, Hong MY, and Carroll RJ: Understanding the Relationship between Carcinogen-induced DNA Adduct Levels in Distal and Proximal Regions of the Colon. Advances in Experimental Medicine and Biology, 537: 105-116, 2003.

Baggerly, KA, Morris JS, and Coombes KR: Reproducibility of SELDI Mass Spectrometry Patterns in Serum: Comparing Proteomic Data Sets from Different Experiments.  Bioinformatics, 20(5):  777-785, 2004.

Sinicrope FA, Half E., Morris JS, Lynch PM, Morrow JD, Levin B, Steinbach G, Hawk ET, Cohen DS, Ayers GD, Stephens LC, FAP Study Group: Cell proliferation and apoptotic indices predict adenoma regression in a placebo-controlled trial of celecoxib in Familial Adenomatous Polyposis (FAP) patients. Cancer Epidemiology, Biomarkers, and Prevention, to appear 2004.

Ajani J, Walsch G, Komaki RR, Morris JS, Swisher SG, Lynch P, Wu TT, Vaporciyan A, Faust JC, Nivers RJ, and Roth J: Preoperative induction CPT-11 and cisplatin chemotherapy followed by chemoradiotherapy in patients with local-regional carcinoma of the esophagus or gastroesophageal junction.  Cancer, to appear 2004.

Hu, J, Yin G, Morris JS, Zhang L, and Wright FA: Entropy and Survival-based Weights to Combine Affymetrix Array Types in the Analysis of Differential Expression and Survival.  To appear in Methods of Microarray Data Analysis III, 2004.

Morris JS, Yin G, Baggerly KA, Wu C, and Zhang L: Pooling Information Across Different Studies and Oligonucleotide Microarray Chip Types to Identify Prognostic Genes for Lung Cancer.  To appear in Methods of Microarray Data Analysis III, 2004. 
 
 
 

ON-GOING RESEARCH SUPPORT 
 

NCI R01 CA107304-01 Morris, Jeffrey (PI), 3/1/2004 – 2/28/2007, NIH, Adaptive Methodology for Functional

   Biomedical Data.

Overall Goals: Develop new methodology for functional data that provides a unifying framework for

   performing nonparametric function estimation & inference for functional data.

Role: Principal Investigator 
 

RFA CA 02-010, Kimmel, Marek (PI), 7/1/2002 - 6/30/2006, NIH, Modeling Lung Cancer: Risks, Progression & Screening.  Cancer Intervention and Surveillance Modeling Network. 

Overall Goals:  To construct a realistic statistical model of lung cancer risk and progression that will make it possible to relate current trends in lung cancer incidence and mortality to past trends in smoking in the US population.

Role:  Statistician 
 

NCI 5P30 CA016672-28, Mendelsohn, John (PI), 7/1/03 – 6/30/2008, NIH, Cancer Center Support Grant, Biostatistics Core

Overall Goals:  The major objectives are to provide biostatistical consultation, collaboration, and resources to clinical laboratory scientists involved in the planning, conduct, analysis and interpretation of research studies.  Research on the biostatistical aspects of clinical and laboratory scientists will also be carried out for problems arising in the course of consultation.  Also, appropriate educational programs in biostatistical methodology will be given to inform interested clinical and laboratory scientists.

Role:  Statistician 
 

American Cancer Society Research Scholar Award, Shureiqi, Imad (PI), 1/1/04 – 12/31/07, 15-Lipoxygenase-1 and Mechanisms of Colorectal Tumorigenesis.

Overall Goals:  This proposal will examine the mechanistic relationship between 15-LOX-1 expression and colorectal tumorigenesis using in vivo and in vitro models of 15-LOX-1 antisense I non-tumorigenic colon cell line (NCM460) and inducible 15-0LOX-1 expression systems in colorectal cancer cells.

Role:  Statistician 
 

NCI RO1 CA098380-01, Li, Donghui (PI), 1/1/04 – 12/31/08, NIH, Molecular Epidemiology of Pancreatic Cancer.

Overall Goals:  To investigate the role of environmental and genetic factors and their interactions in pancreatic cancer.  The environmental factors include dietary exposure to heterocyclic aromatic amines and cigarette smoking.  The genetic factors investigated in this study are carcinogen metabolism and DNA repair genes.

Role:  Statistician 
 

COMPLETED RESEARCH SUPPORT 
 

University of Texas M. D. Anderson Cancer Center Institutional Research Grant, Hassan, Manal (PI), 10/1/01 – 9/30/03.  Hepatitis Virus, Alcohol Exposure and Oxidative Stress.

Overall Goal:  Pilot study to generate preliminary data to demonstrate the interaction between HCV and alcohol in liver and HCC.

Role:  Statistician 
 

University of Texas M. D. Anderson Cancer Center Institutional Research Grant, Hassan, Manal (PI), 9/1/01 – 8/31/03.  Hepatitis Virus, Alcohol Exposure and Oxidative Stress.

Overall Goal:  To determine the level of oxidative stress in relation to etiology and disease status.

Role:  Statistician

PHS 398/2590 (Rev. 05/01) Page _______ Biographical Sketch Format Page

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Use ½-inch MARGINS. Number pages consecutively at the bottom throughout the application. Do not use suffixes such as 3a, 3b.