[share-ebook]METABOLISM BIOCHEMICAL MECHANISMS OF TOXICITYTimbrell JA Principles of Biochemical Toxicology

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This list is intended for the guidance of candidates; it is not intended to indicate required reading. Much of the essential information can be gained from the texts which are indicated. In many cases these also have chapters which cover the various topics which are detailed. If the student finds these texts lacking in sufficient detail and requires extra information in certain areas other references are given under the appropriate headings. Candidates are also advised to consult current toxicology journals for specialised articles. 
 

 
 

Standard Texts:

Anderson D and Conning DM (1993). Experimental Toxicology - The Basic Issues (2^nd edn). London, The Royal Society of Chemistry.

Amdur MO, Doull J and Klaassen CD (1996). Casarett and Doull’s Toxicology. The Basic Science of Poisons (5th edn). McGraw-Hill.

Ballantyne, B, Marrs, TC and Syversen, T (1999). General and Applied Toxicology (2nd edd). London, MacMillan

Hayes AW (2001) Principles and Methods of Toxicology, (4th Edition), Taylor & Francis, London,

Loomis TA and Hayes AW (1996). Loomis’s Essentials of Toxicology (4th edn). San Diego, Academic Press

Niesink RJM, de Vries J and Hollinger MA (1996). Toxicological Principles and Applications. Boca Raton, CRC Press.

Timbrell JA (1997). Study Toxicology through Questions. London, Taylor and Francis.

Wexler P (2005). Encyclopedia of Toxicology, Amsterdam, Elsevier. 
 

 
 

Atterwill CK, Goldfarb P and Purcell W. (1999). Approaches to High Throughput Toxicity Screening. London, Taylor and Francis.

Calabrese EJ (1983). Principles of Animal Extrapolation. New York, Wiley.

Hayes AW (2001). Principles and Methods of Toxicology. New York, Taylor and Francis. 
 

 
 

Aldridge WN (1996). Mechanisms and Concepts in Toxicology.  London, Taylor and Francis

Boelsterli UA (2002). Mechanistic toxicology – the molecular basis of how chemicals disrupt biological targets. London, Taylor and Francis.

Chipman JK (1997). Mechanisms of Cell Toxicity. Advances in Molecular and Cell Biology, Vol. 20 JA1

Denison MS and Helferich WG (1998). Toxicant Receptor Interactions in the Modulation of Signal Tranduction and Gene Expression. London, Taylor and Francis

Puga A and Wallace KB (1998). Molecular Biology of the Toxic Response. London, Taylor and Francis

Timbrell JA (1999). Principles of Biochemical Toxicology (3rd edn). London, Taylor and Francis 
 

 
 

Winter ME (2003). Basic Clinical Pharmacokinetics. Kansas City, Americal College of Clinical Pharmacy.  
 

 
 

Bernishke, K, Garner, FM and Jones TC (1978). Pathology of Laboratory Animals. New York, Springer.

IARC Monograph (Series): Tumours of Laboratory Animals. Lyon, International Association for Research on Cancer.

La Via MF and Hill RB (1980). Principles of Pathobiology (3rd edn). Oxford, Oxford University Press.

Grasso P (2002). Essentials of Pathology for Toxicologists. London, Taylor and Francis.

Haschek W.M. (1998). Fundamentals of Toxicologic Pathology. San Diego, Academic Press

Haschek W, Rousseaux CG, Wallig MA (2001). Handbook of Toxicologic Pathology. Amsterdam, Elsevier

Salisbury J (1997). Molecular Pathology. London, Taylor and Francis.

Turton J and Hooson J (1998). Target Organ Pathology : A Basic Text. London, Taylor and Francis. 
 

 
 

Basketer D, Gerberick F, Kimber I and Willis C (1999). Toxicology of Contact Dermatitis, Chichester, Wiley

Descotes J (1998). Introduction to Immunotoxicology. London, Taylor and Francis.

Environmental Health Criteria (EHC) Series 180 (1996). Principles and methods for assessing direct immunotoxicity associated with exposure to chemicals. Geneva, WHO.

Environmental Health Criteria (EHC) Series 212 (1999). Principles and methods for assessing allergic hypersensitisation associated with exposure to chemicals. Geneva, WHO. 
 

 
 

Brusick DJ (1994). Methods for genetic risk assessment. Boca Raton, CRC Press

Department of Health (1989). Guidelines for the testing of chemicals for mutagenicity. Report of the Committee on Mutagenicity of Chemicals in Food Consumer Products and the Environment. [Report on Health and Social Security Subjects No.35] London, HMSO.

IPCS/WHO (2000). Guidelines for the Monitoring of Genotoxic Effects of Carcinogens in Humans. Mutat Res, 463, 111-172.

UKEMS. Basic mutagenicity tests: UKEMS Recommended Procedures. UKEMS Sub-Committee on Guidelines for Mutagenicity Testing. Report Part I Revised. D Kirkland (Ed). Cambridge, Cambridge University Press, (1990).

UKEMS Supplementary Mutagenicity Tests. UKEMS Recommended Procedures. UKEMS Subcommittee on Guidelines for Mutagenicity Testing Report Part II revised Cambridge University Press (1993). Cambridge

UKEMS. Statistical Evaluation of Mutagenicity Test Data. UKEMS Sub-Committee on Guidelines for Mutagenicity Testing. Report Part III. D. Kirkland (Ed). Cambridge, Cambridge Univ. Press (1989). 
 

 
 

Department of Health (1991). Guidelines for the Evaluation of Chemicals for Carcinogenicity. Report of the Committee on Carcinogenicity of Chemicals on Food, Consumer Products and the Environment. [Report on Health and Social Security Subjects No. 42] London, HMSO.

Garner RC (1991). Human Carcinogen Exposure, Biomonitoring and Risk Assessment. Oxford, IRL Press.

Knudson AG, Stanbridge EJ, Sugimura T, Terada M and Watanabe S (1990). Genetic basis for Carcinogenesis, Tumour Suppressor Genes and Oncogenes. London, Taylor and Francis. 
 

 
 

Bartell SM, Gardner RH and O’Neill, RV (1990). Toxicological Risk in Aquatic Ecosystems. Boca Raton, Lewis Publishers.

Mommsen TP and Moon TW (2005) Environmental Toxicology Amsterdam, Elsevier

Shaw IC and Chadwick J (1998). Principles of Environmental Toxicology. London, Taylor and Francis

Walker CH, Hopkins SP, Sibly RM and Peakall DB (1996). Principles of Ecotoxicology. London, Taylor and Francis

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Hoffbrand AV and Pettit JE (1984). Essential Haematology. Oxford, Blackwell.

Marshall WJ and Bangert SK ( 2004). Clinical Chemistry 5th Edition. Amsterdam,Elsevier

Whitby LG, Smith AF and Beckett GJ (1988). Lecture Notes on Clinical Chemistry (4th edn). Oxford, Blackwell.

Zilva JF Pannall PR and Mayne PD (1988). Clinical Chemistry in Diagnosis and Treatment (5th edn). London, Edward Arnold. 
 

 
 

Anderson D and Russel T (1995). The Status of Alternative methods in Toxicology. London, Royal Society of Chemistry.

Atterwill CK and Steele SE (1998). In Vitro Methods in Toxicology. Cambridge, Cambridge University Press.

Balls, M C (1991). Animals and Alternatives in Toxicology. London, Macmillan.

Goldberg AM, Alternative Methods in Toxicology (Series). New York, Leibert.

Salem H and Katz S (1997). Advances in Alternatives for Safety and Efficacy Testing. New York, Taylor and Francis.

Salem H (1998) Advances in Animal Alternatives. New York,Taylor and Francis 
 

 
 

Olshan AF and Mattieson DR (1994). Male-mediated Developmental Toxicity, Plenum Press, New York.

Robaire B and Hales BF (2003) Advances in Male-mediated Developmental Toxicity. New York, Kluwer/Plenum Publishers

Richardson M (1993). Reproductive Toxicology. Weinheim, VCH.

Sullivan FM, Watkins WJ, Van der Venne M, The Commission of the European Communities (1993). Reproductive Toxicity Vol 1. summary reviews of the Scientific Evidence. 
 

 
 

Barile FA (2003). Clinical Toxicology, Principles and Mechanisms. London, Taylor and Francis.